Selected Publications

  1. Burke-Schinkel SC,  Carrasco-Medina L, Cooper CL, Crawley AM. 2016. Generalized Liver- and Blood-Derived CD8+ T-Cell Impairment in Response to Cytokines in Chronic Hepatitis C Virus Infection. PLOS ONE.. 
  2.  Crawley AM., and Angel JB. 2012. The influence of HIV on CD127 expression and its potential implications for IL-7 therapy. (Invited review article for Semin. Immunol., 24:231-240.
  3. Vranjkovic A., Crawley AM., Patey A., Angel JB. 2012. In vitro HIV Type 1 infection indirectly alters CD127 expression on CD8+ T-cells. AIDS Research and Human Retrovirology. 28:295-298.
  4. Crawley AM., and Angel JB. 2011. Expression of g-chain cytokine receptors on CD8+ T-cells in HIV infection with a focus on IL-7Ra (CD127). Immunol. Cell. Biol. 90:379-387.
  5. *Vranjkovic A., Crawley AM., Patey A., Angel JB. 2011. IL-7-dependent STAT-5 activation and CD8+ T-cell proliferation are impaired in HIV infection. J. Leuk. Biol., 89:499-506.  Note: An editorial introduces this article in its issue: Paiardini M. et al., 2011. J. Leuk Biol. 89:491-3.
  6. O’Connor A., Crawley AM., Angel JB. 2010. The role of IL-7 in memory CD8+CD127+ T-cell function and its impairment in HIV disease. Immunol., 131(4):525-536.
  7. Crawley AM., Vranjkovic A., Young C., Angel JB. 2010. Interleukin-4 downregulates CD127 expression on human thymocytes and mature CD8+ T-cells. Eur. J. Immunol., 40:1396-1407.
  8. Crawley, AM., Faucher S., Angel JB. 2010. Soluble IL-7Ra (sCD127) inhibits IL-7 activity and is increased in HIV infection. J. Immunol., 184:4679-4787.
  9. Faucher S., Crawley AM., Decker W., Sherring A., Bogdanovic D., Ding T., Bergeron M., Angel JB., Sandstrom P. 2009. Development of a Quantitative Bead Capture Assay for Soluble IL-7 Receptor a in Human Plasma. PLoSONE, 4(8): e6690.
  10. Crawley AM., Katz T., Parato KP., Angel JB. 2009. IL-2 receptor g chain cytokines differentially regulate human CD8+CD127+ and CD8+CD127- T-cell division and susceptibility to apoptosis. Int. Immunol., 21: 29-42
  11. Vranjkovic A.*, Crawley AM.* Gee K., Kumar A., Angel JB. 2007. IL-7 decreases IL-7 receptor-α (CD127) expression and induces shedding of CD127 by human CD8+ T cells. Int. Immunol., 19: 1329-1339. (*contributed equally).