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Crawley lab members in bold
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Dec, 2021
BATL: Bayesian annotations for targeted lipidomics Sept, 2021 TLR-4 agonist induces IFN-g production selectively in pro-inflammatory human M1 macrophages through the PI3K-mTOR, p38 and JNK-MAPK activated p70S6K pathway April 2021 Symptoms, pulmonary function and functional capacity four months after COVID-19 Jan, 2021 Selective killing of human M1 macrophages by Smac mimetics alone and M2 macrophages by Smac mimetics and caspase inhibition May, 2020 IL-7 induces sCD127 release and mCD127 downregulation in human CD8+ T cells by distinct yet overlapping mechanisms, both of which are impaired in HIV infection Aug, 2020 Expression of inhibitory receptors on T and NK cells defines immunological phenotypes of HCV patients with advanced liver fibrosis Jan 2020, In vitro hepatitis C virus infection and hepatic choline metabolism Aug, 2019 Dysfunction of bulk circulating CD8+ T-cells in chronic HCV infection is associated with liver disease severity and is unresolved after HCV cure Jul, 2019 Evaluation of safety and effectiveness of Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) Switch followed by Ledipasvir-Sofosbuvir HCV Therapy in HIV-HCV Co-Infection Apr, 2019 Macrophage subsets are dysfunctional in chronic HCV infection and contribute to CD8+ T-cell impairment Mar, 2019 Influence of Ribavirin and the Cirrhotic State on Metabolic Measures in Hepatitis C Direct Acting Antiviral Treatment Recipients Jul, 2018 6th Canadian Symposium on HCV: Delivering a Cure for Hepatitis C Infection: What are the Remaining Gaps? Jan, 2018 Hepatitis C virus core protein reduces CD8+ T-cell proliferation, perforin production and degranulation but increases STAT5 activation Dec, 2017 Increase in soluble IL-7 receptor levels in plasma is associated with improved therapeutic outcome to IL-7 therapy in SIV-infected ART-treated Rhesus macaques Apr, 2016 Influence of female sex on hepatitis C virus infection progression and treatment outcomes. European Journal of Gastroenterology and Hepatology Jun, 2016 Generalized Liver- and Blood-Derived CD8+ T-Cell Impairment in Response to Cytokines in Chronic Hepatitis C Virus Infection Mar, 2012 he influence of HIV on CD127 expression and its potential implications for IL-7 therapy Mar, 2012 In vitro HIV Type 1 infection indirectly alters CD127 expression on CD8+ T-cells Aug, 2011 Expression of g-chain cytokine receptors on CD8+ T-cells in HIV infection with a focus on IL-7Ra (CD127) Apr, 2011 IL-7-dependent STAT-5 activation and CD8+ T-cell proliferation are impaired in HIV infection Dec, 2010 The role of IL-7 in memory CD8+CD127+ T-cell function and its impairment in HIV disease May, 2010 Interleukin-4 downregulates CD127 expression on human thymocytes and mature CD8+ T-cells May, 2010 Soluble IL-7Ra (sCD127) inhibits IL-7 activity and is increased in HIV infection Aug, 2009 Development of a Quantitative Bead Capture Assay for Soluble IL-7 Receptor a in Human Plasma Jan, 2009 IL-2 receptor g chain cytokines differentially regulate human CD8+CD127+ and CD8+CD127- T-cell division and susceptibility to apoptosis Dec, 2007 IL-7 decreases IL-7 receptor-α (CD127) expression and induces shedding of CD127 by human CD8+ T cells |
2021
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